Wow, indeed!

Have never seen that.  The closest to it I have seen is when I hadn't yet learned to turn off auto upgrades and "stole" advanced farms and did not realize it.  My population overage drove down approval and I couldn't figure it out what was happening.  By then it was late enough in the game that I was trying to go quickly through turns and had rally dialed down my micromanagement.

 Actually,  I won this game (also had the plague megaevent later) finally.  There were many close battles so it was a good game;  my good economy allowed me to rush-buy many large-hulled ships on newly conquered planets.  I usually only give up when my ships are being destroyed without enemy damage/losses.

  The disease/plague events cause much unhappiness while they exist.