Sadly, I can't recall the exact name of the program or its author. It was a free program I installed >1yr ago. It operated by creating its own dummy files in key user directories and monitoring them for changes. If any of its files were tampered with the program was supposed to stop everything before any more damage could be done.
Thanks AzDude - I followed your links to perform a clean boot. No lockups after I did the clean boot, and after some testing it turns out what was causing my computer UI to lock up was an old anti-ransomware program I had, not Start10. I've deleted the culprit and all is fine.
I have have the same issue with hard lockups as Billvert describes. I have a Lenovo X1 Yoga. It has all the latest W10 and Lenovo updates. I don't know for sure what is causing the lockup, but one reason to suspect Start10 is it appears that just the Windows UI is locked up, not other programs that may be running. I would like to stop Start10 from starting up so I can see if the problem goes away, but don't see a way in the Start10 configuration to do that. More details: (