Actually - my apologies - this has nothing to do with the graphics (though I do still experience an FPS drop over cities), but it seems every time I click the End Turn button there a 2-5 second pause - the whole game freezes for that long, the turn 'ends' and things continue as normal. Is this... normal? Am I the only one experiencing the issue?

Try unchecking "Enable Auto Saves" under your Game options and see if that helps.

If it does, you can do quick saves using CTRL+S.

That seems to have reduced the end of turn pauses I was experiencing.  I would gladly trade a longer time between saves for not having to experience the pauses every turn.  So put that down on the wishlist - allowing a user to define the number of turns between saves.

I have been seeing the pauses between turns in 1.06 after a couple hundred turns on a Large map with 4 Ridiculous AI. The game actually stopped responding so if you clicked inside the window it'd pop up the Windows "This program stopped responding" error, but would go away after a few seconds when the game woke up. I haven't gotten to that stage in 1.07, though I did send Boogie the old 1.06 save and mentioned that was happening.

Auto save currently saves every turn - so it's deleting a save file, renaming a save file, and then generating a save file.  In addition to all the end of turn processing that is taking place.

You could try doing a quick save (CTRL + S) to see if you notice a pause in the game while it's performing a quick save.  I see a noticeable pause in the game whenever I do it.  So it's definitely a contributor for me - but I'm running an old Pentium IV that should be put out to pasture so I expect it.

This has randomly happened to me. I created a new game and had 5 second pause between turns right off the bat, there was also a very long pause between clicking stuff on the map and the pop up i.e like combat, grabbing goodie  huts. I quit, started a new game and had no pauses, around 50 turns into it and good so far. My 600 turn game has around 7 second pause between turns, don't think I can continue with that kind of delay.

Auto-save made no difference for me either.

SO, now at turn 375 I'm up to almost 10 seconds per turn. 

I realize there is a lot happening per turn - but 10 seconds of waiting every time I hit 'End Turn' is quite a bit that adds up quickly. At this rate my earlier guess of 30 minutes for 500 turns is more like ~70 minutes or so of doing nothing.

http://drop.io/jnj7ypk4971/asset/test-elesav

Save file attached.

Ok - I get the same issue as well - at the end of each battle.  The delay before the battle summary screen comes up - is approaching 3-4 seconds at the best (game at turn 1189) - and has been that way for many, many turns.

Bradley