Process: Rundll32 SPIRunE.dll
from 
Stardock Forums
Stardock Forums
Rundll32 SPIRunE.dll - General Information
Name:
Rundll32 SPIRunE.dll
Publisher
Creative Technology, Ltd.
Product:
SPIRun Endpoints Dynamic Link Library
Default location:
Rundll32 SPIRunE.dll
Rundll32 SPIRunE.dll - Description and Recommendation
Part of the Creative Soundblaster X-Fi driver package. If disabled from startup, some X-Fi functions such as the Crystallizer and CMSS-3D are disabled.
Rundll32 SPIRunE.dll - Uninstall Techniques