Installed a new Graphics card and Multiplicity doesnt work at all??

My graphics card stoped working this weekend so I bought and installed a new one. I updated all the drivers turned on my secondary computer as soon as my cursor hit the edge of the screen on my primary computer it dissapears and won't come back. The keybord sitll functions as it normally does on my primary computer but the only way I have found to get the cursor form the mouse back and usable is to restart the primary computer. I uninstalled and then reinsatlled Multiplicity on both computers but allas the same thing happens still. If some one has an ideas what to do please reply, I have no clue what is going on and I sent a ticket into support but havn't heard back and it's been 5 days?? I like the progam and it has work flawlessly for 2 years I hate to give up on it but I have no clue how to fix it.