Seems if I have several windows open at a time, the Start menu, which should be centered is slight left adjusted. Seems to start after opening the eighth window. It gets worse with each additional app window, moving further left. I only have a single monitor. I can't tell if it's app or only window specific but I believe it's just the number of windows.
Edition Windows 11 Home
Installed on 9/26/2022
OS build 22621.1992
Experience Windows Feature Experience Pack 1000.22644.1000.0
The fix is to turn on the option "Do not offset the menu horizontally to ensure it lines up with the Start button".