I too am experiencing a flicker where the DeskScapes animated background can momentarily be seen "through" another application.
This includes Word, Outlook, and Excel.
If I pause the DeskScapes animation, the flicker stops. Restart the animation and the flicker returns.
I have tried three different video drivers and the problem persists.
I have not seen the problem with Autodesk products or internet browsers, primarily Microsoft applications.
Edition Windows 10 Pro
Installed on 4/5/2021
OS build 19044.1826
Experience Windows Feature Experience Pack 120.2212.4180.0
Video Card/Driver NVIDIA Quadro P4000, 512.96