I don't remember this happening as much before I upgraded to Tiles 2, and even then it was always caused by really old games or ones where the window is implemented weirdly. Now it's happening even for recent games made with Unity or Unreal which Tiles always handled really well.
I've had to get used to needing to close Tiles whenever I open a game and restarting it when I stop playing. And if I'm taking frequent breaks to do something else with the game still running, it gets even more frustrating as I rely on Tiles when otherwise using Windows.
Does Tiles 2 have some new setting that I'm missing which addresses this but is default off?
I'm using W10 btw.