You are kidding right? SHODAN the main protagonist in both the System Shock games. You generic insane AI that likes to tinker with cybernetics and biologics. And sounds utterly fruit loop when it speaks.
Ah, I see now. I never played System Shock 1 or 2.
You should definitely hunt down SS2. SS1 is hard to play (it's from the era of FPSs before mouse controls were really accepted), but SS2 plays like a modern FPS with really, really nice RPG elements.
It's also home to my single favorite moment in gaming, ever. Spoiler below:
Okay ... Can't figure out how this board does spoiler blocking, so ... avert your eyes?
When you're hunting through ... the engineering section on the first ship (IIRC), and you come into the area between two of the "warehouses," and you find the body on the ground. You walk closer, and you get the ghost, where the guy is basically crying and apologizing for not being able to get out, and how he won't let the monsters get him. Then he stands up, makes the sign of the Cross, and kills himself. I still get shivers thinking of it.