Awesome game in all respects, I personally have failed at adjusting my PC to be compatable for multiplayer but hopefully soon I, or someone else can form an inclusive guide, past that this is the single best RTS game I have played.
One already exists

Actually has since before the game's launch

Check out Monk's sticky in the Technical forum, I think he has a link in that thread to his Sins-specific guide (the thread itself is a bit more general).