Near as I can tell, yes you could have multiple copies of the Inn resource/tile and assign each a different ID/visual for a bit of variety the various types of Farm plots the game has is a pretty good example of this.

City tiles might be a bit more difficult, though. Farms are certainly possible, as they can only be built on certain tiles (although it would be the same for each type of plot: ie: the same farm would occur on all pumpkin patches), but other city tiles are unlikely unless there is some built in mechanism for randomizing the tile graphics a bit.

This sounds like a great idea, could help give cities a bit more character and individuality. Might be cool if you could even select from multiple options. So if you are designing a seedy port town, you could select a particular tile set that reflects that concept.