I don't think so. Casuals will usually have already moved on to another game by the time an expansion comes out. They're much less likely to go out and buy them, especially after the first expansion. Plus, once a game has released an expansion it's much more difficult to get anybody with only "casual" interest in the game to buy it because they're likely to feel like it's a larger investment (need to buy original + expansion[s]).
That's actually not true. One of the reasons for expansion packs is that it brings the casual players back to playing the game.
With Demigod, the objective is to have the game evolve so that it supports both casual players and competitive players. So more and more of the updates as we go along will allow casual players to get what they want out of the game while also catering to the competitive players. I wouldn't be surprised to see distinct communities emerge from that.
The pantheon in Demigod at release is really just a test bed. In the long-run, we would love to support things like custom mod versions of Demigod where people can create and set up their own teams and their own tournaments. Meanwhile, casual players will be able to easily get together with friends or just join games where it will find suitable matches based on a number of criteria.
It'll be awhile before all that sort of thing goes in but at least there you have a road map of what we'd like to do.