Don't you use F@H? (folding home)
I have Windows 11, a core i7 9800X and 32 GB of RAM, and a 2080 Super. I have 8GB of RAM, permanently occupied. I have no problem with Deskscape, just with Fence: with ETS and ATS, return to the desktop and blockages. I removed Fence and it works.
You have what you need in terms of equipment to make it work. If it doesn't work, you have your Windows, which is affected. In these cases, I try to repair it. It's very effective. You download the ISO image, put it on your desktop, click on it, go to the disk and setup.exe.
You follow, you pay attention, that the boxes "keep applications, files, etc. are checked. You will end up with a new Windows. I have done it very often.
It's tempting.