I actually replied to a post about this in the Windowblinds forum. I feel that this is the correct forum for this issue.

Ever since the Creators Update it is not possible to navigate the Edge browser while Cursor FX Plus is active. I have 3

computers, all windows 10 64bit that have this same problem. I have to use the default cursor in order to click on anything

or even move up or down the page. (keyboard or mouse) I am a retired old man that really appreciates the extra large 

cursor that Cursor FX provides.