I have used IE (and only IE) since the beginning and will never use another browser (unless being forced to use Safari on my iDevices counts! ).
I run everything and I mean everything in/on my computational devices (Windows or otherwise) from a "least priviledge" frame of thinking. Software developers cannot and in most cases should not be trusted to secure your stuff (even if in most cases it becomes a case of securing yourself from yourself).
Anyone who trusts software "settings" (browser settings/options/addons) or purchases more software to "lock doors" (firewalls etc.) or "clean house" (scanners etc.) and doesn't first subscribe to "least priviledge thinking/operations" is missing the boat on the first and/or best line of defense.
One of these days I will do a nice in-depth write up on what I see as "least priviledge thinking" in the digital world and how I personally have and continue to implement it in my everyday life. For now, searching "least priviledge computing" in a search engine should help those who are still stuck in the "reactionary security" frame of mind to at the very least question some of their daily practices which may be needlessly endangering their systems/data and understand other options quite possibly without the need to purchase more software or change existing software.