I just reloaded an autosave where I had just completed research on Heroes.  I was unable to recruit any level 5 Heroes or go on level 5 Hero Quests as indicated in the tech tree.  This is not normally a problem, therefore, the only thing I can think of is that it must have something to do with the autosave.  I loaded the game I saved after the autosave, and I was able to recruit level 5 heroes and go on level 5 quests as per normal.