Has happened to me numerous times. I once trying to link up my cities with caravans but couldn't because Percipenee (or whom ever she is) had packed caravans in my city centers. There were 3 cities I could not connect. This also has happened with trying to build on a square, such as gold. A hero was on it, neutral, and I couldn't access it for several turns because the sod wouldn't move. Also, if any neutral is in a stack, you can't attack the stack. You also can't access various buildings in your own town if you have a unit on it. It's a bit of a royal pain.