I have the same issue. Seems to be worse with auto save turned on, but turning autosave off doesn't seem to help. It almost seems like it happens when two events pop up at once.
Amazingly frustrating. Not only does it crash the game but it completely freaks out my video card, causing me to reboot. Seriously.
I am on 32 bit XP, have an ATI 3800 HD. I really think is lame to have to post to pastebin, that is the sort of thing you do in beta.
I've updated my drivers AND DirectX.
As a side note, this started for me with the second "Day 0" patch.