Hmmmm.
One of my machines is running an 8600GTS with a fairly aged CPU/MOBO combo (Pentium 805D, if you can believe it!). I've (correction, I HAD) been OC'ing the 8600GTS to 800mhz with no problems, and the performance increase was incredible - turning this old beast into q fairly decent gaming rig.
One night, I played a few games of Demigod, and then decided to try out this game called Atlantica. I don't know if it was some sort of driver initialization conflict (since both games are in Beta), but awhile into that session, my video glitched out hard, and continued to flicker and fragment on the desktop so I rebooted. The next night (I must be dense or something) I did the same thing, Demigod > Atlantica, and it glitched out again, requiring another reboot.
Now, the machine performs quite poorly in all games, acting as if the GPU is overheating. However, according the the MSI Dual Core Center, GPU temp rarely climbs over a rather repid 100°. But at that temp, I start dropping frames like crazy, and the only thing that I can think is that somehow the increased load burned out the PCI-E slot on the MOBO. The other odd thing about this - now streaming video (I watch my 30 Rock and Family guy on Hulu because I don't own a TV) won't play at fullscreen either, without horrible frame loss.
In one way, it's not the end of the world, since it's my second machine, but now it sucks. 
