I expect this max-Missile-Defense/Hyper Computers strategy should work all the better in ToA 2.0, because of the steep weapons costs. Maybe I can do another AAR--and this time, not screw up the screenshots.
It's not just weapons costs that are up, but defense costs, too. Essentially anything that's termed a "military" tech (although I'm unsure at present if hull techs are counted towards this, as I forgot to check). Then again, defense techs are still cheaper than weapons techs, albeit not by as much as they were in DA, so your point still applies somewhat.