I have been playing Sins of a Solar Empire for awhile (I picked it up a little after it released at retail) and I have noticed one thing that really gets on my nerves about the game.
That one thing is that when you install an update to Sins such as the recent 1.05 update, previously saved games no longer work. I believe it would be simple enough to allow previously saved games to continue to work even after updating. Most of the RTS or 4X titles I have played allow for previously saved games from a previous version of the game to work in the game after the game has been updated to a newer version.
It's not a big deal, but it can get annoying - I want to update because of bug fixes and gameplay tweaks, but I don't want to not be able to finish a good round of Sins that I was playing.