depends a lot on your style and if you are planning to go for a particular victory condition, or just see where the game goes.
One configuration I quite liked before 1.1 I went for +1 speed, and 50% military prod so I could quickly produce colony ships + grab planets (+ resources when found early) quickly. Could usually grab huge chunks of the map this way even on suicidal, and win.
the other point would go on luck - It seemed to me (dont know for sure tho) that I got more money-giving anomalies this way which can make a huge difference in early game (esp with the way i play). besides, i like being lucky

certainly not the best (I dont think there can be a best), but it worked for me
not had chance to play 1.1 yet, so maybe this won't work so well now. nice thread btw, will be interesting to see all the different tactics people try
Mark